ABRACAMAL: Elucidating the contribution of malaria relapse components to achieving radical cure
André Machado de Siqueira
Fundação Oswaldo Cruz (Fiocruz)
Project name
ABRACAMAL: Elucidating the contribution of malaria relapse components to achieving radical cure
About
The study proposes to follow patients with malaria in locations with different transmission scenarios to determine the actors related to infection recurrence. For that, clinical follow-up protocols will be applied, as well as molecular biology techniques, medicine quality assessment, treatment adherence, adverse effect frequency and molecular and pharmacogenetics aspects. The project will improve the knowledge about factors associated with recurrence and classify those episodes, making possible to adjust the recommendation on case management.
Published studies
- Towards malaria elimination: a reflection about digital notification modules to improve malaria cases notification speed and follow-up in the Brazilian Amazon region - 05/2024
- Is Brazil reaching malaria elimination? A time series analysis of malaria cases from 2011 to 2023 - 01/2024
- Record Linkage for Malaria Deaths Data Recovery and Surveillance in Brazil - 12/2023
- Assessing the impact of the “malaria supporters project” intervention to malaria control in the Brazilian Amazon: an interrupted time-series analysis - 09/2023
- Variability in white blood cell count during uncomplicated malaria and implications for parasite density estimation: a WorldWide Antimalarial Resistance Network individual patient data meta-analysis - 06/2023
- Malaria time series in the extra-Amazon region of Brazil: epidemiological scenario and a two-year prediction model - 05/2022
- Increased primaquine total dose prevents plasmodium vivax relapses in patients with impaired cyp2d6 activity: report of three cases - 08/2021
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