Who we are

We are a program that aims to invest in innovative research to address the main challenges faced by Brazil´s Unified Health System (SUS).

Launched in 2003 by the Bill & Melinda Gates Foundation, Grand Challenges is a program that invests in high-impact research to solve major health and development challenges. 

Grand Challenges Brazil is a partnership between the Ministry of Health through the Department of Science and Technology (DECIT), the National Council for Scientific and Technological Development (CNPq), and the Bill & Melinda Gates Foundation. The initiative launched its first request for proposals (RFP) in Brazil in 2013: Grand Challenges Brazil: Prevention and Management of Preterm Birth.

From 2014 to 2022, six RFPs were launched on a range of topics, and 69 projects were funded. Many of the results contributed to Brazil´s Unified Health System (SUS) and have the potential to scale up globally.

This website aims to present the work that GC Brazil is rolling out in the country, as well as to follow the results and developments of all funded projects. It is updated by Fiocruz and by the Foundation´s consulting company, Global Health Strategies. To learn more about the Grand Challenges programs in other countries, please access: gcgh.grandchallenges.org.


Establishment of the partnership between the Ministry of Health, Fiocruz, and the Bill& Melinda Gates Foundation and launching of the first RFP


Preterm birth


All Children Thriving


Antimicrobial Resistance

Data Science – First round




Data Science – Second round