Integrating Molecular Surveillance for P.falciparum elimination in Brazil

This project involves a molecular malaria surveillance tool to monitor drug resistance to P. falciparum using the nanopore MinION sequencer platform to identify mutations in PfKelch 13, PfCRT and PfMDR1 genes, and deletions of PfHPR2 and PfHPR3, supporting public health systems to tailor interventions to sustain control and reach (pre)-elimination stages in international borders areas. Translating genomic data to a simple and easy to understand platform for managers will be fundamental to the initiative’s success. A dashboard will be developed that links the molecular data with the local epidemiological data reported in the malaria surveillance system.